Disulfide Linkage Confirmation is a powerful analytical approach used to confirm the presence and structure of disulfide bonds in proteins or peptides. Disulfide bonds are covalent linkages formed between the sulfur atoms of two cysteine residues in a protein, and their identification is crucial for understanding protein folding, stability, and function.
This technique provides valuable information about the number of disulfide bonds, location, and connectivity of disulfide bonds within a protein.
Our LC-MS equipment provides information on localization of disulfide bonds, down to the specific cysteine residues involved and it can identify low-abundance disulfide bonds due to the higher sensitivity of equipment.
Aragen can provide the unified solutions on confirming the Inter and Intra disulfide linkage within the molecule in close collaboration with our customers to meet their requirements.
