Cell-based bioassays are powerful analytical tools used to evaluate the biological activity and functional properties of biomolecules, including proteins, antibodies, peptides, and small molecules. These assays assess how a biomolecule interacts with specific cellular components or signalling pathways, providing valuable insights into its efficacy, potency, and mechanism of action.
Cell-based bioassays are widely used in drug development, and biological molecule product development. They are especially useful when studying complex biological systems that in vitro models might not fully replicate. By incorporating living cells, these assays can mimic the biological context and cellular responses, making them more predictive of in vivo outcomes.
Complement-Dependent Cytotoxicity (CDC) is a key immune effector function in which antibodies activate the complement system to mediate the destruction of target cells. This process is crucial for the immune response against tumors, infected cells, and pathogen-infected cells.
Aragen can provide the unified support on cell-based bioassays in close collaboration with our customers to meet their assay specifications to complies the regulatory requirements.
